With the breakthrough of gene editing and other cutting-edge biotechnology, R&D of cell therapy drugs has become an upsurge in biopharmaceuticals worldwide, especially they have showed huge potential in the diagnosis and treatment of malignant tumors and other diseases. Cell therapy is divided to immune cell therapy and stem cell therapy. As the representative of immune cell therapy, CAR-T therapy is a product of genetic engineering and used to kill the tumors specifically by retransfusion of engineered peripheral blood mononuclear cells (PBMCs) / antologous or allogeneic T cells.

Cell drug is highly effective, its specificity and uniqueness make the preparation process extremely strict, processing efficiency and safety have become the top concern. CAR-T preparation process includes: target cell separation - cell-specific modification - expansion - identification and formulation filling - formulation retransfusion, every step requires standardization, safety and sterility. As a company who has an early concern about immunotherapy market, Sino-Biocan has built preparation tools with independent intellectual property rights in every step of the process, providing unremitting driving force for the development and innovation of cell technology. 

CELL-VOR Automated Cell Separation System 

CELL-VOR automated cell processing system is used for specific separation of target cells using the principle of “density gradient centrifugation” with high precision optical sensors by means of integrating multiple process modules. It can be used for standardized production of multiple cell products, applied in separation of peripheral blood/ cord blood derived mononuclear cells and cord blood/bone marrow/adipose derived stem cells.

CELL-WAV Automated Cell Expansion System 

CELL-WAV automated cell expansion system perfectly meet culture requirements of different volumes by means of tandem connection of one-to-multiple WAVE units. The compatible sterile consumables can real-time monitor key parameters, i.e. pH, DO, during cell culture to realize real-time replenishment and perfusion. It has Clave threaded sterile sampling port and liquid inlet/outlet to ensure constant control and monitoring of cell growth. CELL-WAV is wide applied in expansion and collection of stem cell, immune cell and other cells required for cell therapy and cosmetology. 

Super CELL-VOR Automated High Volume Cell Concentration System

Super CELL-VOR high volume cell concentration system, together with its compatible disposable closed consumables, is used for closed, automated and efficient concentration of high volume cells by means of continuous flow, widely applied in production scales. The sterile consumables can be customized by selecting different connectors, a sampling port is available for all the bags to ensure sampling requirements 

CELL-COL Cell Recovery System

By using dry technology, cell products can be recovered safely and consistently with simple parameter settings, which reduces the contamination risk of the traditional manual water bath method and provides a complete recovery record.